Publications | KearneyLab

2022

Santarella, F., do Amaral, R.J.F.C., Lemoine, M., Kelly, D., Cavanagh, B., Marinkovic, M., Smith, A., Garlick, J., O’Brien, F.J., Kearney, C.J. Personalized Scaffolds for Diabetic Foot Ulcer Healing Using Extracellular Matrix from Induced Pluripotent Stem‐Reprogrammed Patient Cells. Advanced NanoBiomed Materials

Gopalakrishnan, S., Gupta, A., Makabenta, J.M.V., Park, J., Amante, J.J., Chattopadhyay, A.N., Matuwana, D., Kearney, C.J., Rotello, V.M. Ultrasound‐enhanced Antibacterial Activity of Polymeric Nanoparticles for Eradicating Bacterial Biofilms. Advanced Healthcare Materials

McEvoy, N., Patton, D., Curley, G., Boland, F., Kearney, C.J., Hogan, G., Keogh, A., Clarke, J., Moore, Z. Biomarkers for the early detection of pressure ulcers in the intensive care setting: A comparison between sub‐epidermal moisture measurements and interleukin‐1α. International Wound Journal

McEvoy, N., Patton, D., Avsar, P., Curley, G., Kearney, C.J., Clarke, J., Moore, Z. Effects of vasopressor agents on the development of pressure ulcers in critically ill patients: a systematic review. Journal of Wound Care

De Oliveira, F.C.S., do Amaral, R.J.F.C., dos Santos, L.E.C., Cummins, C., Kearney, C.J., Heise, A. Versatility of unsaturated polyesters from electrospun macrolactones: RGD immobilization to increase cell attachment. Journal of Biomedical Materials Research: Part A

2021

Marinkovic, M., Sridharan, R., Santarella, F., Smith, A., Garlick, J.A., Kearney, C.J. Optimization of extracellular matrix production from human induced pluripotent stem cell-derived fibroblasts for scaffold fabrication. Journal of Biomedical Materials Research: Part A

McEvoy, N., Avsar, P., Patton, D., Curley, G., Kearney, C.J., Moore, Z. The economic impact of pressure ulcers among patients in intensive care units. A systematic review. Journal of Tissue Viability

Kimmins, S.D., Hanay, S. B., Murphy, R., O’Dwyer, J., Ramalho, J., Ryan, E.J., Kearney, C.J., O’Brien, F.J., Cryan, S.-A., Fitzgerald-Hughes, D., Heise, A. Antimicrobial and degradable triazolinedione (TAD) crosslinked polypeptide hydrogels. Journal of Materials Chemistry B

Levingstone, T.J., Ali, B., Kearney, C.J., Dunne, N. Hydroxyapatite sonosensitisation of ultrasound-triggered, thermally responsive hydrogels: an on-demand delivery system for bone repair applications. Journal of Biomedical Materials Research: Part B

Ahmad, T., McGrath, S., Sirafim, C., do Amaral, R.J.F.C., Loong Soong, S., Turkistani, S., Santarella, F., Kearney, C.J. Development of Wound Healing Scaffolds with Precisely-Triggered Sequential Release of Therapeutic Nanoparticles. Biomaterials Science
- This article is part of the themed collection: Biomaterials Science Emerging Investigators 2021
- Selected for back cover image

Santarella, F., Garlick, J. A., O’Brien, F.J., Kearney, C.J. The development of tissue engineering scaffolds using matrix from iPS-reprogrammed fibroblasts. Chapter in ‘iPS CELLS : Methods and Protocols 2nd Edition’.

Santarella, F., Simpson, C.R., Lemoine, M., McGrath, S., Cavanagh, B., Smith, A., Murphy, C.M., Garlick, J., O’Brien, F.J., Kearney, C.J. The lubricating effect of iPS-reprogrammed fibroblasts on collagen-GAG scaffolds for cartilage repair applications. Journal of the Mechanical Behavior of Biomedical Materials, 114 (2021)

2020

Jacob, H., Curtis, A.M., Kearney, C.J. Therapeutics on the clock: Circadian medicine in the treatment of chronic inflammatory diseases. Biochemical Pharmacology, 182 (2020)

Amaral, H.R., Wilson, J., do Amaral, R.J.F.C., Pascu, I., de Oliveira, F.C.S., Kearney, C.J., Freitas, J.C.C., Heise, A. Synthesis of bilayer films from regenerated cellulose nanofibers and poly(globalide) for skin tissue engineering applications. Carbohydrate Polymers, 252(15) (2020)

Santarella, F., Sridharan, R., Marinkovic, M., do Amaral, R.J.F.C., Cavanagh, B., Smith, A., Kashpur, O., Gerami-Naini, B., Garlick, J.A., O’Brien, F.J., Kearney, C.J. Scaffolds Functionalized with Matrix from Induced Pluripotent Stem Cell Fibroblasts for Diabetic Wound Healing. Advanced Healthcare Materials, 9(16) (2020)
- Selected as cover article and image

Kočí, Z., Sridharan, R., Hibbits, A.J., Kneafsey, S.L., Kearney, C.J., O’Brien, F.J. The Use of Genipin as an Effective, Biocopmatible, Anti-Inflammatory Cross-Linking Method for Nerve Guidance Conduits. Advanced Biosystems, 4(3) (2020).

Polloni, A.E., Chiardia, V., do Amaral, R.J.F.C., Kearney, C.J., Gorey, B., de Oliveira, D., de Oliveira, J.V., de Araújo, P.H.H., Sayer, C., Heise, A. Polyesters with main and side chain phosphoesters as structural motives for biocompatible electrospun fibres. Polymer Chemistry, 11(12) (2020)

2019

do Amaral, R.J.F.C., Zayed, N.A., Pascu, E.I., Cavanagh, B., Hobbs, C., Santarella, F., Simpson, C.R., Murphy, C.M., Sridharan, R., González-Vázquez, A., O’Sullivan, B., O'Brien, F.J., Kearney, C.J. Functionalising collagen-based scaffolds with platelet-rich plasma for enhanced skin wound healing potential. Frontiers in Bioengineering and Biotechnology, 7 (2019).

do Amaral, R., Cavanagh, B., O’Brien, F.J., Kearney, C.J. Platelet-Derived Growth Factor Stabilises Vascularisation in Collagen-Glycosaminoglycan Scaffolds In Vitro. Journal of Tissue Engineering and Regenerative Medicine, 13(2) (2019)

Ryan, E. J., Ryan, A. J., Philippart, A., Ciraldo, F. E., Hobbs, C., Nicolosi, V., Boccaccini, A. R., Kearney, C. J., O’Brien, F. J. Collagen Scaffolds Functionalised With Copper-Eluting Bioactive Glass Reduce Infection And Enhance Osteogenesis and Angiogenesis In Vitro and In Vivo. Biomaterials, 197 (2019).

Nikravesh, N., Moakes, R. J. A., Azoidis, I., Davies, O. W., Kearney, C. J., Eisenstein, N. C., Grover, L. C., and Cox, S. C. Physical Structuring of Injectable Polymeric Systems to Controllably Deliver Nanosized Extracellular Vesicles. Advanced Healthcare Materials, 8 (2019)

2018

Ryan, A.J., Kearney, C.J., Shen, N., Khan, U., Kelly, A.G., Probst, C., Brauchle, E., Biccai, S., Garciarena, C.D., Vega‐Mayoral, V., Loskill, P., Kerrigan, S.W., Kelly, D.J., Schenke‐Layland, K., Coleman, J.N., O'Brien, F.J. Electroconductive Biohybrid Collagen/Pristine Graphene Composite Biomaterials with Enhanced Biological Activity. Advanced Materials, 30(15) (2018)

Sridharan, R., Ryan, E. J., Kearney, C. J., Kelly, D. J., O'Brien, F. J. Macrophage polarization in response to collagen scaffold stiffness is dependent on crosslinking agent used to modulate the stiffness. ACS Biomaterials Science & Engineering, 5(2) (2018)

Kavanagh, N., Ryan, E.J., Widaa, A., Sexton, G., Fennell, J., O'Rourke, S., Cahill, K.C., Kearney, C.J., O'Brien, F.J., Kerrigan, S.W. Staphylococcal Osteomyelitis: Disease Progression, Treatment Challenges, and Future Directions. Clinical Microbiology Reviews, 31(2) (2018).

2017 and earlier

Gilroy, D.A., Hobbs, C., Nicolosi, V., Buckley, C.T., O’Brien, F.J., Kearney, C.J. Development of magnetically active scaffolds as intrinsically deformable bioreactors. MRS Communications, 1(8) (2017)

de Oliveira, F.C.S., Olvera, D., Sawkins, M.J., Cryan, S.-A., Kimmins, S.D., da Silva, T.E., Kelly, D.J., Duffy, G.P., Kearney, C.J., Heise, A. Direct UV-Triggered Thiol–ene Cross-Linking of Electrospun Polyester Fibers from Unsaturated Poly (macrolactone)s and Their Drug Loading by Solvent Swelling. Biomacromolecules, 18(12) (2017).

do Amaral, R.J.F.C., Almeida, H.V., Kelly, D.J., O’Brien, F.J., Kearney, C.J. Infrapatellar fat pad stem cells: from developmental biology to cell therapy. Stem Cells International, (2017).

Kearney, C.J., Pandit, A. Special Collection: Closing the Gaps in Skin Wound Healing. Tissue Engineering Part A. 22 (5-6): 401 (2016)

Kearney, C.J., Lucas, C.R., O’Brien, F.J., Castro, C.E. DNA Origami: Folded DNA-Nanodevices That Can Direct and Interpret Cell Behavior. Advanced Materials. 28(27): 5509 (2016)

Kennedy, S., Hu, J., Kearney, C. J., Skaat, H., Gu, L., Gentili, M., Vandenburgh, H. Mooney, D.J. Sequential Release of Nanoparticle Payloads From Ultrasonically Burstable Capsules. Biomaterials 75: 91 (2015)
- Highlighted in news for Materials Today. Polymer capsules deliver nanoparticles on time. 28 October 2015.

Kearney, C. J. +, Skaat, H. +, Kennedy, S. M., Hu, J., Darnell, M., Raimondo, T. M., and Mooney, D. J. Switchable Release of Entrapped Nanoparticles From Alginate Hydrogels. Advanced Healthcare Materials, 4(11): 1634 (2015).+Authors contributed equally to this work.
- Highlighted on medgaget.com. “On-Demand Delivery of Drugs from Nanoparticles Using Ultrasound. June 18th 2015.”

Leal, E. C, Carvalho, E., Tellechea, A., Kafanas, A., Tecilazich, F., Kuchibhotla, S., Auster, M. E., Kokkotou, E., Kearney, C. J., Mooney, D. J., LoGerfo, F.W., Pradhan Nabzdyk, L., Veves, A. Substance P Promotes Wound Healing in Diabetes by Modulating Inflammation and Macrophage Phenotype. The American Journal of Pathology, 185(6): 1638 (2015)

Sridharan, R, Cameron, A. R., Kelly, D. J., Kearney, C. J., O'Brien, F. J. Biomaterial Based Modulation of Macrophage Polarization: a Review and Suggested Design Principles. Materials Today, 18(6): 313 (2015).

Maione, A.G., Brudno, Y., Stojadinovic, O., Park, L. K., Smith, A., Tellechea, A., Leal, E.C., Kearney, C.J., Veves, A., Tomic-Canic, M., Mooney, D.J., Garlick, J.A. 3D human tissue models that incorporate diabetic foot ulcer-derived fibroblasts mimic in vivo features of chronic wounds. Tissue Engineering Part C, 21 (5): 499 (2015).

Huebsch, N.+, Kearney, C. J.+, Zhao, X.+, Kim, J., Cezar, C., Suo, Z., Mooney, D. J. Switchable Drug Delivery via ultrasound-triggered disruption and self-healing of reversibly-crosslinked hydrogels. Proceedings of the National Academy of Sciences, 111(27): 9762 (2014). +Authors contributed equally to this work.
- Highlighted in nature.com/scibx. “Cross-linked hydrogels for ultrasound-induced drug delivery.” Scibx 7(30);
- Highlighted dotmed.com. “On demand chemotherapy with self-healing hydrogel”, June 26, 2014.

Brudno, Y., Silva, E. A., Kearney, C. J., Lewin, S., Aizenberg, M., Mooney, D. J. Reloading drug eluting gels through the bloodstream. Proceedings of the National Academy of Sciences, 111 (35): 12722 (2014)
- Highlighted in Nature Nanotech “Drug delivery: Replenishing reservoirs in vivo”, Nature Nanotechnology 9, 874–875 (2014)
- Highlighted as Editor’s choice in Science. “A complimentary refill, yes please” Science 12 September 2014: Vol. 345 no. 6202 pp. 1307-1308.

Shvartsman, D., Storrie-White, H., Lee, K., Kearney, C. J., Brudno, Y., Ho, N., Cezar, C. A., McCann, C. M., Anderson, E., Koullias, J., Tapia, J. C., Vandenburgh, H., Lichtman, J. W., Mooney, D. J. Sustained delivery of VEGF maintains innervation and promotes reperfusion in ischemic skeletal muscles via NGF/GDNF signaling. Molecular Therapy, 22(7):1243 (2014).

Kearney C. J., Mooney, D. J. Insight: Macroscale Delivery Systems for Molecular and Cellular Payloads. Nature Materials, 12: 1004 (2013).

Kearney C. J., Hsu, H.-P., Spector, M. The Use of Extracorporeal Shock Wave-Stimulated Periosteum for Orthotopic Bone Generation. Tissue Engineering Part A, 18(13): 1500 (2012).

Foldager, C. B., Kearney, C. J., Spector, M. Clinical Application of Extracorporeal Shock Wave Therapy in Orthopedics: Focused versus Unfocused Shock Waves. Ultrasound in Medicine and Biology, 38(10): 1673 (2012).

Kearney C. J., Padera, R.F., Hsu, H.-P., Spector, M. Extracorporeal Shock Wave-Induced Proliferation of Periosteal Cells In Vivo. Journal of Orthopaedic Research, 29(10): 1536 (2011).

Zhang, D., Kearney, C. J., Cheriyan, T., Hsu, H.-P., and Spector, M. Extracorporeal Shock Wave Induced Expression of Lubricin in Tendons and Septa. Cell and Tissue Research, 346(2): 255 (2011).

Kearney, C.J., Zhao, Z., Bruet, B.J.F., Radovitzky, R., Boyce, M. C., and Ortiz, C. Nanoscale anisotropic plastic deformation in single crystal aragonite. Physical Review of Letters, 96: 255505 (2006).