![Kearney Lab logo.JPG](https://static.wixstatic.com/media/4bbdd1_a6e77e4804d44f3e9b7b6dd69d5f68f0~mv2.jpg/v1/fill/w_266,h_78,al_c,q_80,usm_0.66_1.00_0.01,enc_auto/Kearney%20Lab%20logo_JPG.jpg)
2022
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Santarella, F., do Amaral, R.J.F.C., Lemoine, M., Kelly, D., Cavanagh, B., Marinkovic, M., Smith, A., Garlick, J., O’Brien, F.J., Kearney, C.J. Personalized Scaffolds for Diabetic Foot Ulcer Healing Using Extracellular Matrix from Induced Pluripotent Stem‐Reprogrammed Patient Cells. Advanced NanoBiomed Materials
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Gopalakrishnan, S., Gupta, A., Makabenta, J.M.V., Park, J., Amante, J.J., Chattopadhyay, A.N., Matuwana, D., Kearney, C.J., Rotello, V.M. Ultrasound‐enhanced Antibacterial Activity of Polymeric Nanoparticles for Eradicating Bacterial Biofilms. Advanced Healthcare Materials
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McEvoy, N., Patton, D., Curley, G., Boland, F., Kearney, C.J., Hogan, G., Keogh, A., Clarke, J., Moore, Z. Biomarkers for the early detection of pressure ulcers in the intensive care setting: A comparison between sub‐epidermal moisture measurements and interleukin‐1α. International Wound Journal
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McEvoy, N., Patton, D., Avsar, P., Curley, G., Kearney, C.J., Clarke, J., Moore, Z. Effects of vasopressor agents on the development of pressure ulcers in critically ill patients: a systematic review. Journal of Wound Care
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De Oliveira, F.C.S., do Amaral, R.J.F.C., dos Santos, L.E.C., Cummins, C., Kearney, C.J., Heise, A. Versatility of unsaturated polyesters from electrospun macrolactones: RGD immobilization to increase cell attachment. Journal of Biomedical Materials Research: Part A
2021
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Marinkovic, M., Sridharan, R., Santarella, F., Smith, A., Garlick, J.A., Kearney, C.J. Optimization of extracellular matrix production from human induced pluripotent stem cell-derived fibroblasts for scaffold fabrication. Journal of Biomedical Materials Research: Part A
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McEvoy, N., Avsar, P., Patton, D., Curley, G., Kearney, C.J., Moore, Z. The economic impact of pressure ulcers among patients in intensive care units. A systematic review. Journal of Tissue Viability
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Kimmins, S.D., Hanay, S. B., Murphy, R., O’Dwyer, J., Ramalho, J., Ryan, E.J., Kearney, C.J., O’Brien, F.J., Cryan, S.-A., Fitzgerald-Hughes, D., Heise, A. Antimicrobial and degradable triazolinedione (TAD) crosslinked polypeptide hydrogels. Journal of Materials Chemistry B
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Levingstone, T.J., Ali, B., Kearney, C.J., Dunne, N. Hydroxyapatite sonosensitisation of ultrasound-triggered, thermally responsive hydrogels: an on-demand delivery system for bone repair applications. Journal of Biomedical Materials Research: Part B
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Ahmad, T., McGrath, S., Sirafim, C., do Amaral, R.J.F.C., Loong Soong, S., Turkistani, S., Santarella, F., Kearney, C.J. Development of Wound Healing Scaffolds with Precisely-Triggered Sequential Release of Therapeutic Nanoparticles. Biomaterials Science
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This article is part of the themed collection: Biomaterials Science Emerging Investigators 2021
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Selected for back cover image
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Santarella, F., Garlick, J. A., O’Brien, F.J., Kearney, C.J. The development of tissue engineering scaffolds using matrix from iPS-reprogrammed fibroblasts. Chapter in ‘iPS CELLS : Methods and Protocols 2nd Edition’.
![Integrating picture.jpg](https://static.wixstatic.com/media/4bbdd1_75c78f9349444ea09d3a1c996c36f85d~mv2.jpg/v1/fill/w_259,h_187,al_c,q_80,usm_0.66_1.00_0.01,enc_auto/Integrating%20picture.jpg)
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Santarella, F., Simpson, C.R., Lemoine, M., McGrath, S., Cavanagh, B., Smith, A., Murphy, C.M., Garlick, J., O’Brien, F.J., Kearney, C.J. The lubricating effect of iPS-reprogrammed fibroblasts on collagen-GAG scaffolds for cartilage repair applications. Journal of the Mechanical Behavior of Biomedical Materials, 114 (2021)
2020
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Jacob, H., Curtis, A.M., Kearney, C.J. Therapeutics on the clock: Circadian medicine in the treatment of chronic inflammatory diseases. Biochemical Pharmacology, 182 (2020)
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Amaral, H.R., Wilson, J., do Amaral, R.J.F.C., Pascu, I., de Oliveira, F.C.S., Kearney, C.J., Freitas, J.C.C., Heise, A. Synthesis of bilayer films from regenerated cellulose nanofibers and poly(globalide) for skin tissue engineering applications. Carbohydrate Polymers, 252(15) (2020)
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Santarella, F., Sridharan, R., Marinkovic, M., do Amaral, R.J.F.C., Cavanagh, B., Smith, A., Kashpur, O., Gerami-Naini, B., Garlick, J.A., O’Brien, F.J., Kearney, C.J. Scaffolds Functionalized with Matrix from Induced Pluripotent Stem Cell Fibroblasts for Diabetic Wound Healing. Advanced Healthcare Materials, 9(16) (2020)
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Selected as cover article and image
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Kočí, Z., Sridharan, R., Hibbits, A.J., Kneafsey, S.L., Kearney, C.J., O’Brien, F.J. The Use of Genipin as an Effective, Biocopmatible, Anti-Inflammatory Cross-Linking Method for Nerve Guidance Conduits. Advanced Biosystems, 4(3) (2020).
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Polloni, A.E., Chiardia, V., do Amaral, R.J.F.C., Kearney, C.J., Gorey, B., de Oliveira, D., de Oliveira, J.V., de Araújo, P.H.H., Sayer, C., Heise, A. Polyesters with main and side chain phosphoesters as structural motives for biocompatible electrospun fibres. Polymer Chemistry, 11(12) (2020)
![ECM Functionalized scaffolds image.jpg](https://static.wixstatic.com/media/4bbdd1_f759f342e5ad4098be3e971d7f2e7edc~mv2.jpg/v1/fill/w_256,h_329,al_c,q_80,usm_0.66_1.00_0.01,enc_auto/ECM%20Functionalized%20scaffolds%20image.jpg)
2019
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do Amaral, R.J.F.C., Zayed, N.A., Pascu, E.I., Cavanagh, B., Hobbs, C., Santarella, F., Simpson, C.R., Murphy, C.M., Sridharan, R., González-Vázquez, A., O’Sullivan, B., O'Brien, F.J., Kearney, C.J. Functionalising collagen-based scaffolds with platelet-rich plasma for enhanced skin wound healing potential. Frontiers in Bioengineering and Biotechnology, 7 (2019).
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do Amaral, R., Cavanagh, B., O’Brien, F.J., Kearney, C.J. Platelet-Derived Growth Factor Stabilises Vascularisation in Collagen-Glycosaminoglycan Scaffolds In Vitro. Journal of Tissue Engineering and Regenerative Medicine, 13(2) (2019)
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Ryan, E. J., Ryan, A. J., Philippart, A., Ciraldo, F. E., Hobbs, C., Nicolosi, V., Boccaccini, A. R., Kearney, C. J., O’Brien, F. J. Collagen Scaffolds Functionalised With Copper-Eluting Bioactive Glass Reduce Infection And Enhance Osteogenesis and Angiogenesis In Vitro and In Vivo. Biomaterials, 197 (2019).
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Nikravesh, N., Moakes, R. J. A., Azoidis, I., Davies, O. W., Kearney, C. J., Eisenstein, N. C., Grover, L. C., and Cox, S. C. Physical Structuring of Injectable Polymeric Systems to Controllably Deliver Nanosized Extracellular Vesicles. Advanced Healthcare Materials, 8 (2019)
2018
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Ryan, A.J., Kearney, C.J., Shen, N., Khan, U., Kelly, A.G., Probst, C., Brauchle, E., Biccai, S., Garciarena, C.D., Vega‐Mayoral, V., Loskill, P., Kerrigan, S.W., Kelly, D.J., Schenke‐Layland, K., Coleman, J.N., O'Brien, F.J. Electroconductive Biohybrid Collagen/Pristine Graphene Composite Biomaterials with Enhanced Biological Activity. Advanced Materials, 30(15) (2018)
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Sridharan, R., Ryan, E. J., Kearney, C. J., Kelly, D. J., O'Brien, F. J. Macrophage polarization in response to collagen scaffold stiffness is dependent on crosslinking agent used to modulate the stiffness. ACS Biomaterials Science & Engineering, 5(2) (2018)
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Kavanagh, N., Ryan, E.J., Widaa, A., Sexton, G., Fennell, J., O'Rourke, S., Cahill, K.C., Kearney, C.J., O'Brien, F.J., Kerrigan, S.W. Staphylococcal Osteomyelitis: Disease Progression, Treatment Challenges, and Future Directions. Clinical Microbiology Reviews, 31(2) (2018).
2017 and earlier
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Gilroy, D.A., Hobbs, C., Nicolosi, V., Buckley, C.T., O’Brien, F.J., Kearney, C.J. Development of magnetically active scaffolds as intrinsically deformable bioreactors. MRS Communications, 1(8) (2017)
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de Oliveira, F.C.S., Olvera, D., Sawkins, M.J., Cryan, S.-A., Kimmins, S.D., da Silva, T.E., Kelly, D.J., Duffy, G.P., Kearney, C.J., Heise, A. Direct UV-Triggered Thiol–ene Cross-Linking of Electrospun Polyester Fibers from Unsaturated Poly (macrolactone)s and Their Drug Loading by Solvent Swelling. Biomacromolecules, 18(12) (2017).
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do Amaral, R.J.F.C., Almeida, H.V., Kelly, D.J., O’Brien, F.J., Kearney, C.J. Infrapatellar fat pad stem cells: from developmental biology to cell therapy. Stem Cells International, (2017).
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Kearney, C.J., Pandit, A. Special Collection: Closing the Gaps in Skin Wound Healing. Tissue Engineering Part A. 22 (5-6): 401 (2016)
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Kearney, C.J., Lucas, C.R., O’Brien, F.J., Castro, C.E. DNA Origami: Folded DNA-Nanodevices That Can Direct and Interpret Cell Behavior. Advanced Materials. 28(27): 5509 (2016)
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Kennedy, S., Hu, J., Kearney, C. J., Skaat, H., Gu, L., Gentili, M., Vandenburgh, H. Mooney, D.J. Sequential Release of Nanoparticle Payloads From Ultrasonically Burstable Capsules. Biomaterials 75: 91 (2015)
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Highlighted in news for Materials Today. Polymer capsules deliver nanoparticles on time. 28 October 2015.
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Kearney, C. J. +, Skaat, H. +, Kennedy, S. M., Hu, J., Darnell, M., Raimondo, T. M., and Mooney, D. J. Switchable Release of Entrapped Nanoparticles From Alginate Hydrogels. Advanced Healthcare Materials, 4(11): 1634 (2015).+Authors contributed equally to this work.
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Highlighted on medgaget.com. “On-Demand Delivery of Drugs from Nanoparticles Using Ultrasound. June 18th 2015.”
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Leal, E. C, Carvalho, E., Tellechea, A., Kafanas, A., Tecilazich, F., Kuchibhotla, S., Auster, M. E., Kokkotou, E., Kearney, C. J., Mooney, D. J., LoGerfo, F.W., Pradhan Nabzdyk, L., Veves, A. Substance P Promotes Wound Healing in Diabetes by Modulating Inflammation and Macrophage Phenotype. The American Journal of Pathology, 185(6): 1638 (2015)
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Sridharan, R, Cameron, A. R., Kelly, D. J., Kearney, C. J., O'Brien, F. J. Biomaterial Based Modulation of Macrophage Polarization: a Review and Suggested Design Principles. Materials Today, 18(6): 313 (2015).
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Maione, A.G., Brudno, Y., Stojadinovic, O., Park, L. K., Smith, A., Tellechea, A., Leal, E.C., Kearney, C.J., Veves, A., Tomic-Canic, M., Mooney, D.J., Garlick, J.A. 3D human tissue models that incorporate diabetic foot ulcer-derived fibroblasts mimic in vivo features of chronic wounds. Tissue Engineering Part C, 21 (5): 499 (2015).
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Huebsch, N.+, Kearney, C. J.+, Zhao, X.+, Kim, J., Cezar, C., Suo, Z., Mooney, D. J. Switchable Drug Delivery via ultrasound-triggered disruption and self-healing of reversibly-crosslinked hydrogels. Proceedings of the National Academy of Sciences, 111(27): 9762 (2014). +Authors contributed equally to this work.
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Highlighted in nature.com/scibx. “Cross-linked hydrogels for ultrasound-induced drug delivery.” Scibx 7(30);
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Highlighted dotmed.com. “On demand chemotherapy with self-healing hydrogel”, June 26, 2014.
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Brudno, Y., Silva, E. A., Kearney, C. J., Lewin, S., Aizenberg, M., Mooney, D. J. Reloading drug eluting gels through the bloodstream. Proceedings of the National Academy of Sciences, 111 (35): 12722 (2014)
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Highlighted in Nature Nanotech “Drug delivery: Replenishing reservoirs in vivo”, Nature Nanotechnology 9, 874–875 (2014)
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Highlighted as Editor’s choice in Science. “A complimentary refill, yes please” Science 12 September 2014: Vol. 345 no. 6202 pp. 1307-1308.
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Shvartsman, D., Storrie-White, H., Lee, K., Kearney, C. J., Brudno, Y., Ho, N., Cezar, C. A., McCann, C. M., Anderson, E., Koullias, J., Tapia, J. C., Vandenburgh, H., Lichtman, J. W., Mooney, D. J. Sustained delivery of VEGF maintains innervation and promotes reperfusion in ischemic skeletal muscles via NGF/GDNF signaling. Molecular Therapy, 22(7):1243 (2014).
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Kearney C. J., Mooney, D. J. Insight: Macroscale Delivery Systems for Molecular and Cellular Payloads. Nature Materials, 12: 1004 (2013).
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Kearney C. J., Hsu, H.-P., Spector, M. The Use of Extracorporeal Shock Wave-Stimulated Periosteum for Orthotopic Bone Generation. Tissue Engineering Part A, 18(13): 1500 (2012).
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Foldager, C. B., Kearney, C. J., Spector, M. Clinical Application of Extracorporeal Shock Wave Therapy in Orthopedics: Focused versus Unfocused Shock Waves. Ultrasound in Medicine and Biology, 38(10): 1673 (2012).
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Kearney C. J., Padera, R.F., Hsu, H.-P., Spector, M. Extracorporeal Shock Wave-Induced Proliferation of Periosteal Cells In Vivo. Journal of Orthopaedic Research, 29(10): 1536 (2011).
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Zhang, D., Kearney, C. J., Cheriyan, T., Hsu, H.-P., and Spector, M. Extracorporeal Shock Wave Induced Expression of Lubricin in Tendons and Septa. Cell and Tissue Research, 346(2): 255 (2011).
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Kearney, C.J., Zhao, Z., Bruet, B.J.F., Radovitzky, R., Boyce, M. C., and Ortiz, C. Nanoscale anisotropic plastic deformation in single crystal aragonite. Physical Review of Letters, 96: 255505 (2006).